We evaluated employment after temporal lobectomy for refractory epilep
sy in 86 patients (3.5 to 8 years of follow-up). Seventy-three patient
s qualified for the work force before and after surgery. Unemployment
rates declined after surgery (18 patients [25%] unemployed before surg
ery, eight patients [11%] unemployed after surgery), and underemployme
nt also tended to diminish. Improvement in occupational status related
strongly to the degree of postoperative seizure relief. Seizure-free
patients fared better (no unemployment, little underemployment) than p
atients with some seizure-free years and some years with seizures afte
r surgery, whose high underemployment level persisted. Patients with s
eizures in each year after surgery fared worst (despite reduced seizur
e frequency), with increased unemployment after surgery. Age at surger
y also influenced vocational outcome in patients who were unemployed b
efore surgery. Historical, educational, cognitive, and behavioral meas
ures did not correlate with vocational outcome. Employment gains came
slowly; unemployed patients took up to 6 years to obtain work after su
rgery. Of 13 students at the time of surgery, 11 have graduated and ni
ne are now employed. We conclude that seizures play a large role in li
miting employment, and that by alleviating seizures, temporal lobectom
y improves employability in people with refractory epilepsy. Surgery t
hereby provides benefit to individuals with epilepsy by increasing fin
ancial independence and to society by reducing unemployment.