IMPROVEMENT OF MULTIFOCAL MOTOR NEUROPATHY DURING LONG-TERM WEEKLY TREATMENT WITH HUMAN-IMMUNOGLOBULIN

In multifocal motor neuropathy (MMN), little is known of the long-term effect of human immunoglobulin (HIG) infusions as a maintenance thera py. We report a patient who improved after an initial HIG infusion of 2 g/kg and continued to improve both clinically and electrophysiologic ally during maintenance HIG treatment consisting of one infusion of 0. 4 g/kg every week. Our findings suggest that maintenance HIG therapy m ay lead to further improvement of MMN, and that more frequent HIG infu sions at a lower dosage may be more effective.