Vc. Karande et al., THE LIMITED VALUE OF HYSTEROSALPINGOGRAPHY IN ASSESSING TUBAL STATUS AND FERTILITY POTENTIAL, Fertility and sterility, 63(6), 1995, pp. 1167-1171
Design: To determine whether the diagnostic accuracy and prognostic va
lue of hysterosalpingography (HSG) could be improved if routine spot f
ilms were replaced by an on-line recorded gynecoradiologic study. Sett
ing: Medical school-affiliated private infertility center. Patients: I
n 1992, a review of 152 infertile women with infertility who demonstra
ted a normal HSG, by standard criteria of spot film evaluation, in 117
(77%). They were further investigated by gynecoradiologic study if th
e HSG revealed asymmetrical tubal filling, an increased perfusion pres
sure, and/or evidence for abnormal tubal spill. In 1993, 47 women with
normal HSG by spot film criteria underwent bilateral selective salpin
gography and were subdivided into those with normal (group I, n = 23)
and abnormal (group II, n = 24) tubal perfusion pressures. Interventio
n: Patients in both study groups then were treated for their infertili
ty independently of pressure perfusion measurements. Main Outcome Meas
ure: Clinical pregnancy rates (PRs) over the ensuing 6 to 10 months. R
esults: Among 117 women with apparently normal spot film HSG, 64 (55%)
demonstrated asymmetrical tubal filling, 32 (27%) demonstrated abnorm
al spillage into the peritoneal cavity, and 55 (47%) demonstrated abno
rmally elevated injection pressures. Among 98 women who underwent bila
teral selective salpingography, 43 (44%) demonstrated bilaterally norm
al tubal perfusion pressures and 55 (56%) showed an abnormally elevate
d pressure in at least one oviduct. Of 47 women that were followed pro
spectively in 1993, patients with normal perfusion pressure (group I)
demonstrated a significantly higher PR than women with elevated tubal
pressure (group II) from 2 months and on after the procedure. Conclusi
ons: Routine spot film HSG is of limited value in assessing tubal stat
us beyond the determination of tubal patency. Especially with regard t
o fertility potential, HSG should be replaced by gynecoradiologic stud
y.