INFREQUENT SITES OF EXTRAMEDULLARY RELAPSE AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION

Authors
VIARD F BILHOUNABERA C MARIT G DURRIEU F DUBUS P MASSERON T BOIRON JM GHARBI MJ SALZES S BROUSTET A REIFFERS J BERNARD P
Citation
F. Viard et al., INFREQUENT SITES OF EXTRAMEDULLARY RELAPSE AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION, Nouvelle revue francaise d'hematologie, 37(2), 1995, pp. 153-157
Citations number
15
Categorie Soggetti
Hematology
Journal title
Nouvelle revue francaise d'hematologie → ACNP
ISSN journal
00294810
Volume
37
Issue
2
Year of publication
1995
Pages
153 - 157
Database
ISI
SICI code
0029-4810(1995)37:2<153:ISOERA>2.0.ZU;2-W
Abstract
In the present report, we describe two cases of rare extramedullary re lapse (skin, muscle) after allogeneic bone marrow transplantation (BMT ). As both patients were male and had received sex mismatched (non T-d epleted) BMT, marrow samples were analysed with a Y-chromosome specifi c probe allowing the sensitive detection of host DNA. The proportion o f host DNA remained low in all post BMT samples from these patients, e ven at the time of extramedullary relapse.