D. Loisance et al., CRITERIA OF PRIORITY ON THE WAITING LIST FOR CARDIAC TRANSPLANTATION, Archives des maladies du coeur et des vaisseaux, 88(4), 1995, pp. 431-436
The limited ressources (in grafts, human and financial resources) inci
ted the authors to carry out a prospective assessment of the value of
assessing adrenergic function (scintigraphy with meta-iodo-benzyl guan
idine, MIBG) for the procedure of inscription on the waiting list of p
atients with cardiac failure awaiting cardiac transplantation. The stu
dy was undertaken from October 1988 to October 1992. Seventy-eight can
didates for transplantation were included in the study. Forty-six pati
ents with a MIBG cardiothoracic ratio less than 120 % were placed on t
he waiting list. In July 1993, 35 had undergone transplantation after
a 5 months delay. Four patients are still awaiting transplantation and
7 died whilst on the waiting list. Thirty two with a MIBG cardiothora
cic ratio greater than 120 % were treated medically : in 14 cases (43
%) this decision was reviewed after 17 +/- 12 months. The clinical cou
rse was stable in the other 18 patients with a follow-up of 46 +/- 18
months (range : 12-72 months). In all, the results of this study show
that a procedure of selection for inscription on the waiting list of p
atients with cardiac failure judged to be good candidates for transpla
ntation based on the value of the MIBG cardiothoracic ratio allows def
errement of inscription of patients at least risk without changing the
chances of survival in the whole population group within a 2 year per
iod.