Background: Health care cost continues to play a dominant role in our
society. Technological advances are expensive, with the possible excep
tion of stereotactic breast biopsy. We must learn other alternatives t
hat give the same diagnostic accuracy at lower cost. The intention of
this study was to find other acceptable alternatives to open excisiona
l breast biopsies. Methods: Patients were referred to Baylor Universit
y Medical Center between May 1990 and June 1992 for stereotactic breas
t biopsy of nonpalpable mammographic abnormalities. Before stereotacti
c biopsy, lesions were categorized into low or high suspicion for mali
gnancy based on screening mammography. Slides were reviewed by a patho
logist and the histological diagnosis was compared with mammographic c
haracterization. Benign histology confirming the low-suspicion mammogr
aphic abnormality demonstrated mammographic and histologic correlation
. Mammographic follow-up was recommended. Results: Two hundred twenty-
five women underwent 250 stereotactic breast biopsies. Malignancy was
diagnosed in 47 patients; the remaining 203 lesions were benign on pat
hological examination and are being followed regularly. Seventy-eight
percent of the lesions were characterized as low suspicion for maligna
ncy, ind 22% were characterized as high suspicion. The average cost sa
vings per lesion using stereotactic biopsy was $1,629. Conclusion: Ste
reotactic breast biopsy is an acceptable, less expensive alternative t
o open excisional biopsy for diagnosing nonpalpable mammographic findi
ngs.