Objectives: Mechanical circulatory support was proposed in patients in
cardiogenic shock, as a bridge to cardiac transplantation or weaning.
The aim of the present study is an analysis of the first 42 cases. Me
thods: The 42 cases included 31 patients in cardiogenic shock unrespon
sive to medical therapy, good cardiac transplant candidates, and 11 pa
tients unweanable off ventricular assist, or in shock in the intensive
care unit. Results are evaluated in terms of transplantability and ho
spital survival. Results: Overall success rate is 67%, ranging from 25
% in previously transplanted patients to 46% following acute myocardia
l infarction and 57% in cardiomyopathy, Age and learning curve played
a significative role. Conclusion: These data suggest that mechanical s
upport improves survival in patients in cardiogenic shock. Earlier imp
lantation should improve the patient outcome.