The fundamental principles of computed tomography (CT), its clinical a
pplications and costs are presented followed by the indications and re
sults in diseases of the mediastinum, the oesophagus, heart and great
vessels, and the lung and pleura. The CT scan can give the precise loc
alization and density of mediastinal tumours and be used to distinguis
h thymomas, goiters, lymph nodes, lymphomas, neurinomas and different
bronchogenic and pleuropericardial cystic formations. The operability
of oesophageal cancer can also be determined. In cardiovascular diseas
es, the CT scan is particularly useful to identify inborn anomalies, a
neurysms, aortic dissection or caval compression or thrombus formation
. In lung diseases, the indications for a CT scan are particularly imp
ortant in broncho pulmonary cancer, tuberculosis, bronchopathies and c
hronic lung diseases. In bronchogenic cancer, for example, the CT scan
is not only a major diagnostic tool but is also particularly useful i
n determining the prognosis and for following the effectiveness of tre
atment. The CT scan can be used to identify both effusions of liquid a
nd gas as well as pleural reactions producing thick membranes of impor
tance for both aetiology and later follow-up. Bronchectasis can be ide
ntified on serial sections where the degree of extension can be measur
ed. CT scan is also indicated in patients with emphysema, both for eva
luating extension and follow-up. Finally the indications and contraind
ications for interventional computed tomography, particularly in guidi
ng needle biopsies, is presented.