FAMILIAL DEFECTIVE APOLIPOPROTEIN-B IS RARE IN HYPERCHOLESTEROLEMIC SOUTH-AFRICAN AFRIKANERS, COLOUREDS AND INDIANS

Authors
RUBINSZTEIN DC COETZEE GA VANDERWESTHUYZEN DR LANGENHOVEN E KOTZE MJ
Citation
Dc. Rubinsztein et al., FAMILIAL DEFECTIVE APOLIPOPROTEIN-B IS RARE IN HYPERCHOLESTEROLEMIC SOUTH-AFRICAN AFRIKANERS, COLOUREDS AND INDIANS, South African medical journal, 85(5), 1995, pp. 355-357
Citations number
23
Categorie Soggetti
Medicine, General & Internal
Journal title
South African medical journal → ACNP
ISSN journal
02569574
Volume
85
Issue
5
Year of publication
1995
Pages
355 - 357
Database
ISI
SICI code
0256-9574(1995)85:5<355:FDAIRI>2.0.ZU;2-Q
Abstract
The frequency of familial defective apolipoprotein B-100 (FDB) was ass essed among hypercholesterolaemic Afrikaners, coloureds and Indians. P atients selected for screening did not carry any of the founder or com mon LDL-receptor mutations known to be associated with these groups. N o FDB was detected and the mutation is therefore a rare cause of hyper cholesterolaemia in these South African populations.