A STEREOSELECTIVE SYNTHESIS OF MEDIUM-SIZED CYCLIC ETHERS BY THE INTRAMOLECULAR CYCLIZATION OF LINEAR HYDROXYALKYL-PROPARGYLIC ALCOHOLS ASSISTED BY CO-2(CO)(8)

Authors
PALAZON JM MARTIN VS
Citation
Jm. Palazon et Vs. Martin, A STEREOSELECTIVE SYNTHESIS OF MEDIUM-SIZED CYCLIC ETHERS BY THE INTRAMOLECULAR CYCLIZATION OF LINEAR HYDROXYALKYL-PROPARGYLIC ALCOHOLS ASSISTED BY CO-2(CO)(8), Tetrahedron letters, 36(20), 1995, pp. 3549-3552
Citations number
44
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
20
Year of publication
1995
Pages
3549 - 3552
Database
ISI
SICI code
0040-4039(1995)36:20<3549:ASSOMC>2.0.ZU;2-6
Abstract
A highly efficient, mild and general cyclization reaction of hydroxy e xo-(propargyl)Co-2(CO)(6) cations leading to medium-sized (6 to 9 memb ered) cyclic ethers is described. The reaction is highly stereoselecti ve when defined stereocenters are encountered in the linear precursor, providing a way to obtain fused cyclic ethers in their enantiomeric f orms.