PALLIDOTOMY FOR PARKINSONS-DISEASE

Authors
LAITINEN LV
Citation
Lv. Laitinen, PALLIDOTOMY FOR PARKINSONS-DISEASE, Neurosurgery clinics of North America, 6(1), 1995, pp. 105-112
Citations number
71
Categorie Soggetti
Clinical Neurology",Neurosciences,Surgery
Journal title
Neurosurgery clinics of North America → ACNP
ISSN journal
10423680
Volume
6
Issue
1
Year of publication
1995
Pages
105 - 112
Database
ISI
SICI code
1042-3680(1995)6:1<105:PFP>2.0.ZU;2-C
Abstract
Ventroposterolateral pallidotomy was used in the surgical treatment of 259 patients suffering from intractable Parkinson's disease. Pallidot omy was equally effective against tremor, rigor, bradykinesia, and the L-dopa-induced dyskinesias. The effect of surgery seemed to be long-l asting, and side effects were rare. The author believes that the benef icial effect of pallidotomy is based on interruption of striopallidal and pallidosubthalamic pathways.