EMERGENCE OF HIGH-LEVEL FLUOROQUINOLONE-RESISTANT ESCHERICHIA-COLI INBANGLADESH

Fifteen fluoroquinolone-resistant strains of Escherichia coli were iso lated from different clinical specimens of paediatric patients, 2 year s after introduction of the drugs into Bangladesh. However, none of th ese patients had any definite history of treatment with fluoroquinolon es. MICs of these strains to different antibiotics were determined by the broth microdilution method recommended by the Working Party of BSA C. Strains were highly resistant to all drugs except ceftriaxone. Stud y indicates a high frequency of fluoroquinolone-resistant E. coli stra ins among the clinical isolates which is possibly related to fluoroqui nolone introduction.