OPTICALLY-ACTIVE (S)-KETONE-CYANOHYDRIN AND (R)-ALDEHYDE-CYANOHYDRIN VIA AN (R)-OXYNITRILASE-CATALYZED TRANSCYANATION - CHEMOENZYMATIC SYNTHESES OF 2-CYANOTETRAHYDROFURAN AND 2-CYANOTETRAHYDROPYRAN

Authors
MENENDEZ E BRIEVA R REBOLLEDO F GOTOR V
Citation
E. Menendez et al., OPTICALLY-ACTIVE (S)-KETONE-CYANOHYDRIN AND (R)-ALDEHYDE-CYANOHYDRIN VIA AN (R)-OXYNITRILASE-CATALYZED TRANSCYANATION - CHEMOENZYMATIC SYNTHESES OF 2-CYANOTETRAHYDROFURAN AND 2-CYANOTETRAHYDROPYRAN, Journal of the Chemical Society, Chemical Communications, (10), 1995, pp. 989-990
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
10
Year of publication
1995
Pages
989 - 990
Database
ISI
SICI code
0022-4936(1995):10<989:O(A(V>2.0.ZU;2-5
Abstract
(R)-Oxynitrilase catalyses the enantioselective decyanation of racemic ketone cyanohydrins and the enantioselective addition of HCN to omega -bromoaldehydes in one step.