MENOPAUSAL GENUINE STRESS URINARY-INCONTINENCE TREATED WITH CONJUGATED ESTROGENS PLUS PROGESTOGENS

Objective: The aim of the study was to investigate clinically and urod ynamically the effects of hormonal replacement in the treatment of gen uine stress urinary incontinence in postmenopausal females. Methods: C linical and urodynamic variables of 30 postmenopausal women with genui ne stress urinary incontinence were evaluated after 3 months' treatmen t with conjugated estrogens plus progestogens. Urodynamic evaluations were performed in all patients before and after treatment. Results: Fo rty-six percent of the patients treated medically were judged to be cu red and 43% were judged to be markedly improved. Maximum urethral clos ure pressure, maximum cystometric capacity and mean flow were signific antly increased. Residual urine and diurnal and nocturnal voluntary mi cturition were markedly decreased (P < 0.05). Conclusion: We conclude that hormone replacement in the form of conjugated estrogens plus prog estogens results in the clinical and urodynamic improvement of genuine stress urinary incontinence in postmenopausal women.