Study Design. A case of an intramedullary spinal cord abscess is prese
nted. The literature on this subject is carefully reviewed. Objectives
. To give an overview of clinical presentation, radiographic examinati
on, pathogenesis, treatment, and outcome of intramedullary spinal cord
abscesses, Cases presented in the literature are arranged and the fin
dings summarized. Summary of Background Data. Intramedullary spinal co
rd abscesses are rare. Most frequently, single cases were reported, fo
llowed by a short discussion. All previously reported cases were revie
wed. Methods. After an extensive literature search, all cases of an in
tramedullary spinal cord abscess (totaling 93 patients), including our
s, were reviewed. Incidence, clinical presentation, neuroradiologic in
vestigations, treatment, and pathogenesis are discussed. Results. Intr
amedullary spinal cord absesses are rare. The presentation can be very
confusing, mimicking thoracic or abdominal diseases. Magnetic resonan
ce imaging is the best diagnostic technique, although the findings are
not pathognomonic. Appropiate antibiotic therapy after surgical drain
age is warranted. If left untreated, the outcome is bleak. Whereas mos
t cultures remain sterile (38.7%), Staphylococcus or Streptococcus spe
cies are involved frequently (23.7% and 17.2%), Conclusions. Although
intramedullary spinal cord abscess is a rare disease, every spine surg
eon should have knowledge of its existence because misjudgment and def
erring adequate treatment may lead to an unfavorable outcome.