SYNTHESIS AND BIOLOGICAL-ACTIVITY OF PYRIMIDOBENZODIAZEPINE DERIVATIVES - NEW RING-SYSTEMS - TRIAZOLO-PYRIMIDOBENZODIAZEPINES AND TETRAZOLO-PYRIMIDOBENZODIAZEPINES
A. Dlugosz, SYNTHESIS AND BIOLOGICAL-ACTIVITY OF PYRIMIDOBENZODIAZEPINE DERIVATIVES - NEW RING-SYSTEMS - TRIAZOLO-PYRIMIDOBENZODIAZEPINES AND TETRAZOLO-PYRIMIDOBENZODIAZEPINES, Die Pharmazie, 50(3), 1995, pp. 180-182
New triazolo- and tetrazolo-pyrimidobenzodiazepines were synthesized a
nd screened as anti-HIV, anticancer and immunosuppressive agents. Some
of the compounds showed immunosuppressive activity, similar to or str
onger than that of cyclosporine A.