SYNTHESIS AND BIOLOGICAL-ACTIVITY OF PYRIMIDOBENZODIAZEPINE DERIVATIVES - NEW RING-SYSTEMS - TRIAZOLO-PYRIMIDOBENZODIAZEPINES AND TETRAZOLO-PYRIMIDOBENZODIAZEPINES

Authors
Citation
A. Dlugosz, SYNTHESIS AND BIOLOGICAL-ACTIVITY OF PYRIMIDOBENZODIAZEPINE DERIVATIVES - NEW RING-SYSTEMS - TRIAZOLO-PYRIMIDOBENZODIAZEPINES AND TETRAZOLO-PYRIMIDOBENZODIAZEPINES, Die Pharmazie, 50(3), 1995, pp. 180-182
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
ISSN journal
00317144
Volume
50
Issue
3
Year of publication
1995
Pages
180 - 182
Database
ISI
SICI code
0031-7144(1995)50:3<180:SABOPD>2.0.ZU;2-H
Abstract
New triazolo- and tetrazolo-pyrimidobenzodiazepines were synthesized a nd screened as anti-HIV, anticancer and immunosuppressive agents. Some of the compounds showed immunosuppressive activity, similar to or str onger than that of cyclosporine A.