ROLE OF ALIPHATIC-ACIDS IN THE BIOSYNTHESIS OF VERMICULIN IN PENICILLIUM-VERMICULATUM

Authors
PROKSA B FUSKA J
Citation
B. Proksa et J. Fuska, ROLE OF ALIPHATIC-ACIDS IN THE BIOSYNTHESIS OF VERMICULIN IN PENICILLIUM-VERMICULATUM, Die Pharmazie, 50(3), 1995, pp. 215-216
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
50
Issue
3
Year of publication
1995
Pages
215 - 216
Database
ISI
SICI code
0031-7144(1995)50:3<215:ROAITB>2.0.ZU;2-C
Abstract
The diolode macrolide vermiculin (1) together with the three unsaturat ed aliphatic ketoacids vermiculinic (2), vermiculic (3) and 4-deoxover miculic acid (4) were isolated from the cultivation broth of Penicilli um vermiculatum. Biotransformation of 2 and 3 with growing and resting cells of P. vermiculatum was studied. We suppose, that 2 which is for med from 3, is the ultimate progenitor of 1.