REACTION OF IMINES OF AMINOANTHRAQUINONES WITH FORMALDEHYDE AND ALKENES

Authors
GREGOIRE PJ MELLOR JM MERRIMAN GD
Citation
Pj. Gregoire et al., REACTION OF IMINES OF AMINOANTHRAQUINONES WITH FORMALDEHYDE AND ALKENES, Tetrahedron, 51(21), 1995, pp. 6133-6144
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
51
Issue
21
Year of publication
1995
Pages
6133 - 6144
Database
ISI
SICI code
0040-4020(1995)51:21<6133:ROIOAW>2.0.ZU;2-C
Abstract
By reaction of mono- and di-aminoanthraquinones with formaldehyde and diverse electron rich alkenes in acetonitrile in the presence of trifl uoroacetic acid cyclocondensation affords a series of tetrahydroquinol ines. The resulting tetra-, penta- and hepta-cyclic products all conta in the anthraquinone sub-structure. Aspects of regio- curd stereo-sele ctivity are discussed and the potential of this series of aminoanthraq uinones for metal ion chelation and binding in DNA are noted.