FLUCONAZOLE FOR REFRACTORY OROPHARYNGEAL CANDIDIASIS IN AIDS PATIENTS

Oropharyngeal candidiasis is a major lesion in HIV-infected patients. Effective antifungal therapy is required to prevent weight loss, nutri tional compromise, and systemic infection. The response to oral flucon azole in patients refractory to prior topical or systemic antifungal t herapy was evaluated. A case of oropharyngeal candidiasis in a patient with advanced AIDS that was refractory to topical clotrimazole and or al itraconazole, but responded to oral fluconazole therapy, is reporte d. Oral fluconazole should be considered the primary treatment for oro pharyngeal candidiasis in the HIV-infected population with AIDS status .