The authors describe the normal variations in the buccal space and pre
sent the range of buccal space pathologic conditions seen on computed
tomographic (CT) and magnetic resonance (MR) images, In a series of 50
patients studied with CT and 30 with MR imaging, the visualization an
d measurement of the normal facial expression and buccinator muscles,
parotidomasseteric fascia, parotid duct, accessory parotid tissue, and
facial neurovascular bundle were statistically equivalent, The size o
f the buccal fat pad was statistically the same from side to side with
in a given patient, Normal lymph nodes were rarely discernible from th
e facial neurovascular bundles, In a series of 26 patients with unsusp
ected buccal space masses, salivary gland tumors were the most common
masses, Less frequently, benign lesions (eg, hemangioma and dilated pa
rotid ducts) and soft-tissue malignancies (eg, sarcoma) manifested as
buccal space masses, Occasionally, a cheek mass of uncertain cause pro
ved to be lymphadenopathy; however, adenopathy is more commonly associ
ated with clinically evident, deeply infiltrating facial neoplasms, Kn
owledge of the anatomic variations and expected abnormalities of the b
uccal space is useful for the radiologist interpreting facial CT or MR
images.