XB U-CADHERIN MESSENGER-RNA CONTAINS CYTOPLASMIC POLYADENYLATION ELEMENTS AND IS POLYADENYLATED DURING OOCYTE MATURATION IN XENOPUS-LAEVIS/

Authors
KUHL M WEDLICH D
Citation
M. Kuhl et D. Wedlich, XB U-CADHERIN MESSENGER-RNA CONTAINS CYTOPLASMIC POLYADENYLATION ELEMENTS AND IS POLYADENYLATED DURING OOCYTE MATURATION IN XENOPUS-LAEVIS/, Biochimica et biophysica acta, N. Gene structure and expression, 1262(1), 1995, pp. 95-98
Citations number
28
Categorie Soggetti
Biology,Biophysics,"Biothechnology & Applied Migrobiology
Journal title
Biochimica et biophysica acta, N. Gene structure and expression → ACNP
ISSN journal
01674781
Volume
1262
Issue
1
Year of publication
1995
Pages
95 - 98
Database
ISI
SICI code
0167-4781(1995)1262:1<95:XUMCCP>2.0.ZU;2-5
Abstract
Cytoplasmic polyadenylation elements (CPE) are distinct sequence motif s in the 3'-untranslated region of mRNAs. They control translation of these RNAs by cytoplasmic polyadenylation. We show that the mRNA of th e cell adhesion molecule XB/U-cadherin contains two CPE motifs, With o ocyte maturation this mRNA becomes polyadenylated and increasingly rec ruited into the polysomal fraction. Our results give evidence that CPE s of the XB/U-cadherin mRNA are responsible for the XB/U-cadherin prot ein increase during oocyte maturation.