Ys. Oh et al., ISOLATION AND CHARACTERIZATION OF THE GENE ENCODING THE DROSOPHILA-MELANOGASTER TRANSCRIPTIONAL ELONGATION-FACTOR, TFIIS, Biochimica et biophysica acta, N. Gene structure and expression, 1262(1), 1995, pp. 99-103
We have characterized a genomic clone encoding the Drosophila melanoga
ster transcriptional elongation factor, TFIIS. The coding region of th
e TFIIS gene is interrupted by a short intron. The potential promoter
region, deduced from the determination of the transcription start poin
t (tsp), lacks distinct TATAAA or CCAAT box consensus sequences. South
ern analysis and the in situ hybridization to chromosomes suggests tha
t it is single-copy gene which is localized to the 35B region on the l
eft arm of the second chromosome.