THERE ARE A limited number of previously reported cases involving the
use of radiation therapy for sarcoid of the brain. The case of a 22-ye
ar-old man with a thalamic/posterior third ventricle sarcoid mass that
grew despite steroid medication is presented. The patient was treated
with external beam radiation to a total dose of 20 Gy, with 2-Gy frac
tions over 14 elapsed days. A complete radiographic response was achie
ved 4 months after radiation was completed. Radiographic follow-up thr
ough 8 months postradiation shows no evidence of disease recurrence. F
ractionated radiation therapy in low-to-moderate doses appears to be e
fficacious in steroid-refractory sarcoid of the brain.