S. Harino et al., INDOCYANINE GREEN VIDEOANGIOGRAPHIC FINDINGS IN CHOROIDAL METASTATIC TUMOR, Graefe's archive for clinical and experimental ophthalmology, 233(6), 1995, pp. 339-346
Background. Indocyanine green videoangiography (ICGV) has recently adv
anced and become widely available as a clinical tool. We tested the ef
ficacy of ICGV in evaluating metastatic choroidal tumors. Methods: ICG
V using Topcon 50-IA was performed in five patients with clinically di
agnosed choroidal metastatic tumors. The findings were compared with t
hose of conventional fluorescein angiography (FAG). Results: Compared
with FAG, ICGV demonstrated more smooth and regular hypofluorescent le
sions, precisely indicating the exact size of the tumor. In all cases,
no tumor vessels were found. The choroidal vascular integrity around
the tumors was observed. FAG, however, was more sensitive in detecting
the tumor development than ICGV when the extent of the hypofluorescen
t lesion could be seen clearly in the early phase. FAG provided more i
nformation regarding retinal pigment epithelial dysfunction in the out
er blood retinal barrier overlying the tumor. Conclusion: Since ICGV e
nables visualization of tumors through the retina, it is very useful,
particularly in cases of associated secondary retinal detachment aroun
d the tumors. ICGV combined with FAG provides more precise assessment
of the tumors themselves and their response to treatment than FAG alon
e.