Y. Nakagawa et al., ACTIVITY OF ECDYSONE ANALOGS IN ENHANCING N-ACETYLGLUCOSAMINE INCORPORATION INTO THE CULTURED INTEGUMENT OF CHILO-SUPPRESSALIS, Steroids, 60(5), 1995, pp. 401-405
Ecdysone analogs with various side chains at the 17-position of the st
eroid structure enhanced the incorporation of N-acetylglucosamine as 2
0-hydroxyecdysone into the cultured integument prepared from Chilo sup
pressalis. Their activity in terms of the concentration required to gi
ve 50% of the maximum response varied with the structure. Piperonyl bu
toxide, an inhibitor of oxidation metabolism, did not enhance the in v
itro effect of the compounds. The order of potency was ponasterone A >
20-hydroxyecdysone > cyasterone > inokosterone > makisterone A >> ecd
ysone.