THE REACTION OF CARBON-DISULFIDE WITH DIETHYL 3-AMINO-2-CYANO-2-PENTEN-1,5-DICARBOXYLATE - A CONVENIENT SYNTHESIS OF POLYFUNCTIONALLY SUBSTITUTED THIOPHENES AND THEIR FUSED DERIVATIVES

Authors
SHERIF SM ABDELSAYED NI ELKOUSY SM MOHAREB RM
Citation
Sm. Sherif et al., THE REACTION OF CARBON-DISULFIDE WITH DIETHYL 3-AMINO-2-CYANO-2-PENTEN-1,5-DICARBOXYLATE - A CONVENIENT SYNTHESIS OF POLYFUNCTIONALLY SUBSTITUTED THIOPHENES AND THEIR FUSED DERIVATIVES, Monatshefte fuer Chemie, 126(5), 1995, pp. 601-608
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Monatshefte fuer Chemie → ACNP
ISSN journal
00269247
Volume
126
Issue
5
Year of publication
1995
Pages
601 - 608
Database
ISI
SICI code
0026-9247(1995)126:5<601:TROCWD>2.0.ZU;2-1
Abstract
Carbon disulfide added to the active methylene group in 1 in basic DMF at room temperature to yield the non-isolable 1:1 adduct 2. In-situ c yclization of the latter with some alpha-bromo compounds afforded the corresponding polyfunctionally substituted thiophenes 5. The reactivit y of 5 towards a variety of reagents was studied. Chemical and spectro scopic evidences for the structure of the new compounds are provided.