Two cases of solitary nodules on the skin of the trunk of young adults
showing a peculiar pattern of proliferation of blood vessels and a mi
xed inflammatory infiltrate with predominance of polyclonal plasma cel
l infiltration are presented. Follow-up of these patients after comple
te surgical excision revealed no recurrence. We interpreted the lesion
s within the morphologic spectrum of plasma cell infiltrates of the sk
in to be reactive and/or hyperplastic, which we term primary cutaneous
angioplasmocellular hyperplasia.