THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF ENEDIYNE MINOR-GROOVE BINDING HYBRIDS

Authors
WITTMAN MD KADOW JF LANGLEY DR VYAS DM ROSE WC SOLOMON W ZEIN N
Citation
Md. Wittman et al., THE SYNTHESIS AND BIOLOGICAL-ACTIVITY OF ENEDIYNE MINOR-GROOVE BINDING HYBRIDS, Bioorganic & medicinal chemistry letters, 5(10), 1995, pp. 1049-1052
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
5
Issue
10
Year of publication
1995
Pages
1049 - 1052
Database
ISI
SICI code
0960-894X(1995)5:10<1049:TSABOE>2.0.ZU;2-B
Abstract
The potential for increasing the antitumor potency of a synthetic bicy clic enediyne by attaching a DNA recognition element has been investig ated and the hybrids evaluated for antitumor activity.