MALIGNANT MIXED TUMOR OF THE SKIN MALIGNANT CHONDROID SYRINGOMA

Two cases of malignant mixed tumor of skin were studied, one of which demonstrated regional metastasis. The immunohistochemical features of these 2 neoplasms and of the 2 malignant mixed tumors previously descr ibed in Western Australia indicate that these neoplasms show eccrine d ifferentiation and suggest their origin from both the secretory and du ctal segments of the gland. The histological criteria of malignancy ar e discussed, with particular reference to those features which indicat e malignant potential in neoplasms which otherwise lack overt morpholo gical criteria of malignancy.