Ts. Roper et al., FETOMATERNAL ALLOIMMUNE THROMBOCYTOPENIA ASSOCIATED WITH ANTI-HPA-5A - THE FIRST AUSTRALIAN CASE, Pathology, 26(3), 1995, pp. 294-295
Maternal alloantibodies to platelet specific antigens are a rare but i
mportant cause of severe thrombocytopenia in the fetus and neonate. Fe
to-Maternal Alloimmune Thrombocytopenia (FMAT) is most often due to an
ti-HPA-1a (PLA-1) or anti-HPA-5b (Bra). Anti-HPA-5a (Brb) however is e
xtremely uncommon, with only 4 cases previously described. We report t
he first Australian case of fete-maternal alloimmune thrombocytopenia
due to anti-HPA-5a.