T. Gulliford et al., POPULARITY OF LESS FREQUENT FOLLOW-UP FOR BREAST-CANCER IN RANDOMIZEDSTUDY - INITIAL FINDINGS FROM THE HOTLINE STUDY, BMJ. British medical journal, 314(7075), 1997, pp. 174-177
Objective: To compare the experiences of patients with breast cancer w
ho were conventionally monitored with those in whom routine follow up
was restricted to the time of mammography. Design: Randomisation to co
nventional schedule of clinic visits or to visits only after mammograp
hy, Both cohorts received identical mammography and were invited to te
lephone for immediate appointments if they detected symptoms. Setting:
Combined breast clinic Chelsea and Westminster Hospital. Subjects: 21
1 eligible outpatients with a history of breast cancer. Main outcome m
easures: Acceptability of randomisation, interim use of telephone and
general practitioner, satisfaction with allocation to follow up. Resul
ts: Of 211 eligible patients, 196 (93%) opted for randomisation in the
study, Of these, 55 were under 50 years, 78 were diagnosed fewer than
five years before, 90 had stage T2-4 tumours, and 71 had involved axi
llary nodes, Patients who did not participate were more likely to be u
nder 50 years, to be two to five years after diagnosis, and to have ha
d aggressive primary disease, Twice as many patients in both groups ex
pressed a preference for reducing rather than increasing follow up, No
increased use of local practitioner services or telephone triage was
apparent in the cohort randomised to less frequent follow up by specia
lists. Conclusions: Reducing the frequency of routine follow up has so
far proved popular among patients with breast cancer at standard risk
in this cohort. A multicentre study is needed to determine the effect
iveness and cost-effectiveness of routine follow up with respect to di
sease outcomes.