PURPOSE: To describe the epidemiologic, clinical, and imaging features
of cat-scratch disease (CSD) to facilitate prompt recognition and non
invasive diagnosis of this condition. MATERIALS AND METHODS: Eight oth
erwise healthy patients with pet cats presented with the subacute onse
t of epitrochlear, axillary, or groin masses. All underwent cross-sect
ional imaging with computed tomography (CT) (n = 1) or magnetic resona
nce (MR) imaging (n = 7). Five patients underwent radiography of the e
lbow. RESULTS: In all patients, MR imaging and CT showed a poorly defi
ned soft-tissue mass with extensive surrounding edema in an efferent l
ymphatic distribution. Radiography revealed only soft-tissue edema in
two patients and an ill-defined soft-tissue mass with soft-tissue edem
a in three patients. Six patients underwent biopsy; the findings of al
l pathologic specimens supported the diagnosis of CSD. No patients und
erwent serologic evaluation. All patients were asymptomatic within 4 w
eeks of beginning antibiotic therapy. CONCLUSION: CSD should be consid
ered in all patients with upper extremity or head and neck adenopathy
and a history of cat exposure. Although generally not required for dia
gnosis, cross-sectional imaging will reveal a mass with surrounding ed
ema in an area of lymphatic drainage.