PLASMA AMINO-ACID IMBALANCE IN PATIENTS WITH LUNG AND BREAST-CANCER

Authors
CASCINO A MUSCARITOLI M CANGIANO C CONVERSANO L LAVIANO A ARIEMMA S MEGUID MM FANELLI FR
Citation
A. Cascino et al., PLASMA AMINO-ACID IMBALANCE IN PATIENTS WITH LUNG AND BREAST-CANCER, Anticancer research, 15(2), 1995, pp. 507-510
Citations number
36
Categorie Soggetti
Oncology
Journal title
Anticancer research → ACNP
ISSN journal
02507005
Volume
15
Issue
2
Year of publication
1995
Pages
507 - 510
Database
ISI
SICI code
0250-7005(1995)15:2<507:PAIIPW>2.0.ZU;2-2
Abstract
In order to evaluate whether different solid tumors may specifically i nfluence plasma free amino acid (PFAA) profile, PFAA were analysed in seventy-four patients with lung (41 patients) and breast cancer (33 pa tients) and 28 healthy subjects. In lung cancer patients a significant reduction of gluconeogenic amino acids, threonine, serine, glycine an d a significant increase of free tryptophan and glutamic acid was foun d. In breast cancer patients a significant increase of ornithine, glut amic acid and free tryptophan was found. The comparison of PFAA profil es between lung and breast cancer suggests that different tumors have a different influence on the host's PFAA pattern.