INDICATIONS FOR LAPAROSCOPIC PELVIC LYMPH-NODE DISSECTION IN THE STAGING OF PROSTATE-CANCER

Laparoscopic pelvic lymph node dissection is increasing in popularity, in the absence of validated surgical indications. This retrospective study was performed to identify those patients who would benefit from laparoscopic pelvic lymphadenectomy. The case notes of 50 patients who underwent bilateral open pelvic lymphadenectomy with frozen section e xamination were reviewed. The patients were staged clinically as havin g A2 (16), B1 (20) and B2 (14) prostate cancer. Except for the two pat ients who had macroscopically involved pelvic lymph nodes at operation , all proceeded to total prostatectomy. Six patients were found to hav e positive pelvic nodes. Of the six, four patients were clinical stage B2, one was B1 and one was A2. The Gleason score of two of these six patients was greater than seven. The prostate specific antigen (PSA) l evels correlated more with high tumour volume (i.e. grade C) rather th an with D1 disease. Frozen section at the time of lymphadenectomy had a false negative rate of 2 of 6. We conclude that laparoscopic pelvic lymph node dissections (LPLND) should be performed where there is a hi gh likelihood of nodal disease, viz. bulky tumours, poorly differentia ted histology and a high PSA reading. We consider that such selective use of LPLND optimizes its diagnostic utility while minimizing its unn ecessary application.