One hundred and forty Hong Kong Chinese students were surveyed early i
n the second year of their medical education (year 2), and compared wi
th 138 students surveyed prior to beginning their first year of medica
l school and with 74 non-medical university students in their second y
ear. In year 2 students, distress as reflected in their scores on anxi
ety and depression self-report scales was high, and these students rep
orted greater utilization of health professional services as compared
with the other two groups. In year 2 students, concerns related to the
medical school environment and curriculum, and whether one has the en
durance and ability to be successful were significant correlates with
depression and anxiety. Loss of opportunity to maintain social and rec
reational sources of gratification correlated with anxiety. There was
no difference between the sexes with regard to the development of anxi
ety and depression symptoms. Academically less successful students rep
orted somewhat higher levels of depressive ideation and symptomatology
. Trait anxiety correlated with the development of distress, while opt
imism protected against the development of distress. Active coping sty
les and positive reinterpretation as a coping strategy correlated nega
tively with distress, while wishful thinking correlated positively wit
h distress. These findings emphasize the need for greater attention to
the psychological well-being of doctors-in-training, in Hong Kong as
in the Western world. These findings should be further explored in lon
gitudinal studies, and may be helpful in designing intervention and su
pport programmes for vulnerable students.