Jo. Jorgensen et al., IS LAPAROSCOPY ASSOCIATED WITH A LOWER RATE OF POSTOPERATIVE ADHESIONS THAN LAPAROTOMY - A COMPARATIVE-STUDY IN THE RABBIT, Australian and New Zealand journal of surgery, 65(5), 1995, pp. 342-344
This trial set out to test the hypothesis that there is no difference
in the incidence of intra-abdominal adhesions after a stereotyped intr
aperitoneal injury created via laparoscopy or laparotomy. Twenty New Z
ealand White rabbits had a 2 x 2 cm area of peritoneum stripped off th
eir caecum and adjacent parietal peritoneum, either by laparotomy or l
aparoscopy. Outcome was assessed by the incidence of adhesions to the
test site and the wound. There was no difference in the rate of adhesi
ons at the test site in the two groups. The rate of adhesions to the w
ound was different in the two groups (70% laparotomy, 0% laparoscopy;
P = 0.003). In a rabbit model, comparing laparoscopy and laparotomy in
a strictly controlled operative environment, a stereotyped intraperit
oneal injury results in similar rates of postoperative adhesions. Lapa
roscopy is, however, associated with a much lower incidence of wound a
dhesion. The potential for postoperative adhesions is real after lapar
oscopic surgery.