THE PROTECTIVE EFFECT OF A SMALL AMOUNT OF FISH ON CORONARY HEART-DISEASE MORTALITY IN AN ELDERLY POPULATION

Background. A protective effect of a small amount of fish an coronary heart disease (CHD) mortality has been established in observational st udies in middle-aged people. In the present study this association was investigated in the elderly. Methods. in 1971 CHD risk factors were m easured in 272 people born before 1907. They belonged to a general pra ctice in Rotterdam, the Netherlands and were followed for 17 years. Th e cross-check dietary history method was used to obtain information on fish consumption. Results. During the follow-up period 58 people died from CHD, 67 from cancer and 187 from all causes. In 1971 about 60% o f the elderly ate fish and 40% did not eat fish. Multivariate Cox prop ortional hazards analyses, taking the confounding effect of major risk factors into account, showed an inverse relation between fish consump tion and 17-year CHD mortality. The risk ratio (RR) for fish eaters co mpared with no-fish eaters was significantly different from unity (RR = 0.51, 95% CI : 0.29-0.89). Cancer and total mortality were not relat ed to fish consumption. Conclusion. The results from the present study suggest that the protective effect of a small amount of fish in relat ion to CHD observed in middle-aged people seems also to be present in the elderly.