EFFECTS OF VITAMIN-A-DEFICIENCY ON VITAMIN-E

Effects of vitamin A deficiency on vitamin E were evaluated in two dif ferent situations in which the vitamin A intake was notably reduced. O n the one hand, dogs on an equilibrated diet were submitted to intesti nal resection; hence vitamin A was poorly absorbed, compared with a co ntrol group. On the other hand, deficit of vitamin A was provoked in r ats feeding them with a vitamin A-deficient diet. In both cases vitami n A plasma levels were decreased on comparing them with the correspond ing control groups. In these two cases symptoms of vitamin A deficienc y were observed as loss of muscular mass and nephrolithiasis. It is in teresting to point out that when vitamin A was depleted by either of t he methods, the vitamin E plasma level noticeably increased.