OBJECTIVE: To demonstrate the magnetic resonance imaging (MRI) appeara
nce of the brain in patients with clinical brain death. PATIENTS AND M
ETHODS: High-field (1.5-T) MRI was performed on five patients who were
subsequently proven clinically brain dead. Conventional T-1-weighted
and T-2-weighted imaging was performed. RESULTS: MRI exhibited similar
features for all of the patients: loss of the subarachnoid spaces of
the brain; slow now in the intracavernous and cervical internal caroti
d arteries; and loss of flow void in the small and large intracranial
arteries, as well as in the major intracranial venous sinuses. The dif
ferentiation between grey and white matter in the brain was preserved,
although the brain had a ''supernormal'' appearance due to the absenc
e of cerebrospinal fluid and arterial pulsations. These findings have
not been observed in MRI of comatose patients who were not clinically
brain dead. CONCLUSION: With the advent of MRI-compatible ventilators
and noninvasive monitoring, which facilitate imaging of patients under
intensive care, MRI may offer another method of confirming the clinic
al diagnosis of brain death.