B. Archimowiczcyrylowska et al., CLINICAL EFFECT OF BUCKWHEAT HERB, RUSCUS EXTRACT AND TROXERUTIN ON RETINOPATHY AND LIPIDS IN DIABETIC-PATIENTS, PTR. Phytotherapy research, 10(8), 1996, pp. 659-662
In this study the effect of a buckwheat herb and a Ruscus extract prep
aration, compared with troxerutin, are described with respect to ophth
almological and biochemical parameters in patients with non-proliferat
ive diabetic retinopathy, During the study period of 3 months, 60 diab
etic patients were divided into three equal groups: in group I troxeru
tin was given, in group II Ruscus extract and in group III buckwheat h
erb was administered. At the beginning and on the last day of the stud
y, each patient was subjected to ophthalmological and clinical biochem
istry, The amplitude of oscillating potentials was decreased in patien
ts receiving troxerutin, but increased in group II and group III, Regr
ession of changes located in the fundus of the eye was demonstrated in
23.1%-27.8% of ail treated patients, however deterioration in 5.6% of
patients given troxerutin and in 3.3% of subjects treated with buckwh
eat herb was observed at the same time, No cases with progression of a
bnormalities in the fundus of the eye were found in group II, Moreover
, troxerutin seemed to be less effective, especially when oscillating
potentials were concerned. The use of buckwheat herb for the prophylax
is and treatment of diabetic patients, suffering from retinopathy is r
ecommended.