EFFECT OF AQUEOUS EXTRACT OF BRICKELLIA-VERONICAEFOLIA ON THE GASTROINTESTINAL-TRACT OF GUINEA-PIG, RATS AND MICE

Authors
Citation
Rm. Perez, EFFECT OF AQUEOUS EXTRACT OF BRICKELLIA-VERONICAEFOLIA ON THE GASTROINTESTINAL-TRACT OF GUINEA-PIG, RATS AND MICE, PTR. Phytotherapy research, 10(8), 1996, pp. 677-679
Citations number
10
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
ISSN journal
0951418X
Volume
10
Issue
8
Year of publication
1996
Pages
677 - 679
Database
ISI
SICI code
0951-418X(1996)10:8<677:EOAEOB>2.0.ZU;2-Z
Abstract
The aqueous extract of Brickellia veronicaefolia inhibited gastric emp tying time in rats and intestinal motility in mice, both effects were manifested in a dose-related fashion. The crude extract inhibited the contractions induced by acetylcholine and histamine concentration-depe ndently in the guinea-pig ileum, In the castor oil diarrhoea test, the extract showed 90% protection from diarrhoea at 150 mg/kg.