ANTIMICROBIAL ACTIVITY OF CONSTITUENTS ISOLATED FROM LYCHNOPHORA-SALICIFOLIA (ASTERACEAE)

Authors
MIGUEL OG LIMA EO MORAIS VMF GOMES STA DELLEMONACHE F CRUZ AB CRUZ RCB CECHINEL V
Citation
Og. Miguel et al., ANTIMICROBIAL ACTIVITY OF CONSTITUENTS ISOLATED FROM LYCHNOPHORA-SALICIFOLIA (ASTERACEAE), PTR. Phytotherapy research, 10(8), 1996, pp. 694-696
Citations number
14
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
10
Issue
8
Year of publication
1996
Pages
694 - 696
Database
ISI
SICI code
0951-418X(1996)10:8<694:AAOCIF>2.0.ZU;2-R
Abstract
Lychnophora salicifolia (Asteraceae), a native Brazilian medicinal pla nt used in folk medicine against some diseases, revealed the presence of two known caryophyllene derivatives, in a satisfactory yield: lychn opholic acid 1 and acetyl lychnopholic acid 2. These compounds exhibit ed antifungal activity by the agar diffusion method, and antibacterial activity by the methods of diffusion and minimum inhibitory concentra tion (MIC). However, compound 2 was more potent than 1, suggesting tha t the acetyl group is responsible for antimicrobial activity.