EFFECTS OF HYPERICUM-CALYCINUM L EXTRACT ON THE CENTRAL-NERVOUS-SYSTEM IN MICE

Hypericum species have been used as herbal remedies for the therapy of various neurological disorders. In the present study, the effects of Hypericum calycinum on the central nervous system were investigated us ing various behavioural models including swimming time, locomotor acti vity, tail-flick and hole-board experiments. According to the results obtained, it was found that the extract prepared from H. calycinum is as effective as the antidepressant drugs, desipramine and trimipramine , which were used for comparison with this plant extract in animal mod els.