Sk. Dubey et Ds. Holmes, BIOLOGICAL CYANIDE DESTRUCTION MEDIATED BY MICROORGANISMS, World journal of microbiology & biotechnology, 11(3), 1995, pp. 257-265
Many microorganisms have an inherent capacity to degrade the toxic org
anic compounds that enter the environment as a result of pollution and
natural activities. Significant degradation of these compounds may ta
ke many years and it is frequently necessary to consider methods that
can accelerate this process. There have been several demonstrations of
enhanced biological degradation, of toxic wastes, both in the laborat
ory and under field conditions. The prospects for enhanced biological
cyanide degradation are reviewed. Compared with bench-scale processes,
there are very few reports of field-scale processes for cyanide biore
mediation. The implementation of such field-scale degradation requires
inputs from biology, hydrology, geology, chemistry and civil engineer
ing. A conceptual framework is emerging that can be adapted to develop
new processes for bioremediation of toxic organic wastes. In terms of
cyanide biodegradation, this framework incorporates identification of
microbes, determination of the optimal conditions for degradation, es
tablishment of the metabolic pathways involved in cyanide degradation,
identification and localization of the genes involved, identification
of suitable microbial strains for practical application and developme
nt of practical engineering processes. The present review addresses th
e progress that has been made in each of these aspects of cyanide biod
egradation. IL also examines the existing field applications of biolog
ical cyanide degradation and makes recommendations for future research
.