5-AMINOLEVULINIC ACID PRODUCTION BY CHLORELLA SP DURING HETEROTROPHICCULTIVATION IN THE DARK

Authors
SASAKI K WATANABE K TANAKA T HOTTA Y NAGAI S
Citation
K. Sasaki et al., 5-AMINOLEVULINIC ACID PRODUCTION BY CHLORELLA SP DURING HETEROTROPHICCULTIVATION IN THE DARK, World journal of microbiology & biotechnology, 11(3), 1995, pp. 361-362
Citations number
7
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
World journal of microbiology & biotechnology → ACNP
ISSN journal
09593993
Volume
11
Issue
3
Year of publication
1995
Pages
361 - 362
Database
ISI
SICI code
0959-3993(1995)11:3<361:5APBCS>2.0.ZU;2-L
Abstract
5-Aminolevulinic acid (ALA) was produced aerobically in the dark durin g growth on glucose by a newly isolated Chlorella sp. When levulinic a cid (20 mM), a competitive inhibitor of ALA dehydratase, was added rep eatedly to the medium, about 1.5 mM of ALA was produced extracellularl y. Glutamate (30 mM) added with levulinic acid (20 mM, given repeatedl y) enhanced ALA production up to 1.9 mM, indicating that ALA might be synthesized via the C-5 pathway.