Purpose: To determine the pulpal biocompatibility of Prisma Universal
Bond 2 (PUB-2). Materials and Methods: Class V preparations were made
in eight subhuman monkeys to approximately 1 mm from the pulp. In Grou
p 1, the enamel was etched, the primer was placed and dried, PUB 2 was
painted, and Prisma-Fil inserted. In Group 2, the cavity floor was co
vered with visible light-cured Dycal followed by the steps as in group
1. In Group 3, IRM was used as a negative control. In Group 4, MQ55 s
ilicate cement was used as a positive control. The animals were sacrif
iced at 5, 25, and 60 days and the teeth processed for histological ev
aluation. Results: After 5 days, a mild reaction of little concern, wh
ich had dissipated in the 25- and 60-day groups, was observed. The mat
erial compared favorably to the negative control.