We describe an atypical MRI appearance of multiple sclerosis (MS). Les
ions characterized on T2-weighted images by a well-defined rim of incr
eased signal intensity and a concentric region of higher signal intens
ity were seen in 6 of 132 patients with MS. On T1-weighted images thes
e lesions were evident as regions of low signal intensity, often with
a rim of contrast enhancement or increased signal intensity. These app
earances tended to be shown by new, evolving lesions.