We reviewed the MRI features in eight patients with spinal epidural ly
mphoma (clinically primary in 4 patients); one patient had multiple le
sions. The cervical spine was involved in one patient, the thoracolumb
ar spine in 5 and the sacrum in two. Mean longitudinal extension of th
e epidural lesion was 2.6 vertebral segments. The tumours were homogen
eously isointense with the spinal cord on T1-weighted images and isoin
tense or hyperintense on proton-density and T2-weighted images. The sp
inal cord was compressed in four patients but showed signal changes in
only one. In five patients the lesions communicated through the inter
vertebral foramina with paravertebral soft tissue masses. In all but o
ne of the patients diffuse signal changes in the vertebral body marrow
consistent with osteolytic or osteoblastic changes were identified ad
jacent to or at distance from the epidural lesion. Vetebral collapse w
as observed in two patients.