MINERALIZING MICROANGIOPATHY - CT AND MRI

Mineralizing microangiopathy, a distinctive histopathologic process in volving the microvasculature of the central nervous system (CNS), is u sually seen following combined radiation and chemotherapy for the trea tment of CNS neoplasms in childhood. CT typically demonstrates calcifi cation within the basal ganglia and subcortical white matter. The area s of calcification may give paradoxically increased signal on T1-weigh ted MRI due to a surface-relaxation mechanism, and decreased signal on T2-weighted images.