MEDIATORS OF INFLAMMATION AND THE TREATMENT OF BACTERIAL-MENINGITIS

Authors
TUOMANEN E
Citation
E. Tuomanen, MEDIATORS OF INFLAMMATION AND THE TREATMENT OF BACTERIAL-MENINGITIS, Current opinion in infectious diseases, 8(3), 1995, pp. 218-223
Citations number
NO
Categorie Soggetti
Infectious Diseases
Journal title
Current opinion in infectious diseases → ACNP
ISSN journal
09517375
Volume
8
Issue
3
Year of publication
1995
Pages
218 - 223
Database
ISI
SICI code
0951-7375(1995)8:3<218:MOIATT>2.0.ZU;2-B
Abstract
Issues in the management of bacterial meningitis have focused on pneum ococcal infection. Cell walls appear to induce inflammation differentl y from endotoxins. Adjunctive therapeutics, including carbohydrates, p eptides, and antibodies, target vascular abnormalities as well as leuk ocyte adhesion. New therapeutic recommendations suggest no fluid restr iction and invoke caution when combining dexamethasone with vancomycin for highly beta-lactam-resistant pneumococcal disease.